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Long-term protection against malaria

Long-term protection against malaria

Good news. Research shows that long-term protection against malaria is indeed possible. Previously it was thought that this was not possible.

Two and a half years ago, ten volunteers participated in an experimental immunization method against malaria from the UMC St. Radboud. The subjects used the malaria drug chloroquine . for several months and were exposed to the bite of several infected malaria mosquitoes several times during the same period.

No symptoms
The researchers re-exposed six of the original ten volunteers to mosquitoes after two and a half years. , with the same malaria parasites with which the volunteers were originally infected. And as it turned out:four of the six test subjects showed a complete protection see. A blood infection was also prevented by their immune response. The two other volunteers also showed a defense response , but it was no longer strong enough to treat a blood infection with malaria to stop.

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Big Breakthrough
The researchers consider the experiment to be a major breakthrough in eliciting a long-term protection against the disease † "The generally accepted idea that built-up protection against malaria also disappears relatively quickly, can be thrown into the trash because of this research," says research leader Robert Sauerwein in the American trade journal The Lancet

Unfortunately, this method cannot yet be applied equally to everyone. A follow-up investigation . should therefore also be carried out come. “We need to answer a few other important questions first,” Sauerwein says. 'After two and a half years, our volunteers were infected with the same malaria strain which was used for the first, original infection. In practice, people are infected by various malaria strains.'

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